SECUAH 2018 > González-Cofrade etal 2018
dianas | Vol 7 No 1 | 2018 | e201803
Molecular basis for the pharmacological activity of terpenes
Universidad Complutense de Madrid
lagonz11@ucm.es; lauragoncof@gmail.com
III Congreso de Señalización Celular, SECUAH 2018.
20-22 de marzo, 2018. Universidad de Alcalá. Alcalá de Henares, Madrid. España.
Sesión de paneles
Resumen
Natural products have represented an excellent source for drug discovery and development. Among them, diterpenes display many pharmacological properties with therapeutic potential. A series of labdane diterpenes derivatives from solidagenone (isolated from the rhizomes of Solidago chilensis) have been tested for antiinflammatory activity in targets related to the inflammatory process. Uncontrolled inflammation could lead to serious disorders due to the overproduction of inflammatory mediators, in consequence of uncontrolled inflammasome activation and the up-regulation of pro-inflammatory enzymes, playing critical roles in numerous pathological conditions.
Cita: González-Cofrade L, Cuadrado I, Hortelano S, de-las-Heras B (2018) Molecular basis for the pharmacological activity of terpenes. Actas del III Congreso de Señalización Celular, SECUAH 2018. 20-22 de marzo, 2018. Universidad de Alcalá. Alcalá de Henares, Madrid. España. Sesión de paneles. dianas 7 (1): e201803. ISSN 1886-8746 (electronic) journal.dianas.e201803. URI http://hdl.handle.net/10017/15181
Copyright: ©2018 González-Cofrade L, Cuadrado I, Hortelano S, de-las-Heras B. Some rights reserved. Este es un artículo open-access distribuido bajo los términos de una licencia de Creative Commons Reconocimiento-NoComercial-SinObraDerivada 4.0 Internacional. http://creativecommons.org/licenses/by-nc-nd/4.0/
